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RAS BiologyБиофизика Biophysics

  • ISSN (Print) 0006-3029
  • ISSN (Online) 3034-5278

The Effect of Gel Materials Based on Collagen and Taxifolin Derivatives on the Healing of Burn Wounds Induced by Acetic Acid

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PII
S30345278S0006302925040216-1
DOI
10.7868/S3034527825040216
Publication type
Article
Status
Published
Authors
Yu.V. Shatalin
  • Affiliation: Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences
V.S. Shubina
  • Affiliation: Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences
Volume/ Edition
Volume 70 / Issue number 4
Pages
809-817
Abstract
The aim of the work was to evaluate the effect of gel materials containing pentaglutarate of taxifolin and a conjugate of taxifolin with glyoxylic acid on the healing of skin wounds caused by acetic acid. It was shown that collagen materials containing polyphenols accelerated re-epithelialization and formation of granulation tissue compared with the control (collagen alone). The data obtained indicate that taxifolin derivatives can be considered as promising agents that not only cross-link collagen molecules, but also have a wound-healing effect. In turn, materials based on collagen and these polyphenols can be considered as dual purpose materials: as wound-healing agents and as a delivery system of biologically active substances to the area of injury.
Keywords
гелевые материалы на основе коллагена полифенолы ранозаживляющие свойства индуцированный уксусной кислотой химический ожог
Date of publication
13.12.2025
Year of publication
2025
Number of purchasers
0
Views
39

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