- PII
- S00063029250820082-1
- DOI
- 10.31857/S00063029250820082
- Publication type
- Article
- Status
- Published
- Authors
- Volume/ Edition
- Volume 70 / Issue number 2
- Pages
- 295-304
- Abstract
- Bacteriophage endolysins are part of a lytic enzymes complex responsible for the destruction of the bacterial cell wall peptidoglycan. In this paper, the dynamic properties of bacteriophage T5 single-domain endolysin and the multi-domain endolysin PlyG of gamma phage are studied using molecular dynamics and normal mode analysis. The mechanism of activation of bacteriophage T5 endolysin by calcium and the discovery of a fundamental difference in the dynamic features of single-domain and multi-domain endolysins are explained.
- Keywords
- эндолизин молекулярная динамика анализ нормальных мод активация кальцием динамические особенности белков
- Date of publication
- 24.10.2025
- Year of publication
- 2025
- Number of purchasers
- 0
- Views
- 18
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