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RAS BiologyБиофизика Biophysics

  • ISSN (Print) 0006-3029
  • ISSN (Online) 3034-5278

Essential Role of Disproportionation Reaction of Nitric Oxide Molecules in Their Functioning Mechanism in Living Organisms

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PII
S0006302925010214-1
DOI
10.31857/S0006302925010214
Publication type
Review
Status
Published
Authors
A. F Vanin
  • Affiliation: Semenov Federal Research Center of Chemical Physics, Russian Academy of Sciences
Volume/ Edition
Volume 70 / Issue number 1
Pages
174-180
Abstract
The article considers the question of why nitrosyl ligands in dinitrosyl iron complexes with thiol-containing ligands which are proposed as a “working form” of endogenous nitric oxide (NO) in living organisms are presented equally in dinitrosyl iron complexes as NO molecules and nitrosonium (NO+) cations? It has been shown that such type of presentation is determined by the mechanism of dinitrosyl iron complexes formation from NO molecules, loosely bound bivalent iron and thiol-containing compounds in living organisms. The disproprtionation reaction between NO molecules bound in pairs with Fe2+ ion plays the main role in this process. Regarding thiol-containing ligands they ensure the stabilization of nitrosonium cations arising in NO disproprtionation reaction.
Keywords
оксид азота динитрозильные комплексы железа катион нитрозония реакция диспропорционирования
Date of publication
24.10.2025
Year of publication
2025
Number of purchasers
0
Views
19

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